Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | Set_03_truncNotch_versus_normalThy.phenotype_truncNotch_versus_normalThy.cls #truncNotch_versus_normalThy.phenotype_truncNotch_versus_normalThy.cls #truncNotch_versus_normalThy_repos |
| Phenotype | phenotype_truncNotch_versus_normalThy.cls#truncNotch_versus_normalThy_repos |
| Upregulated in class | normalThy |
| GeneSet | NCI_REELIN SIGNALING PATHWAY |
| Enrichment Score (ES) | -0.8164906 |
| Normalized Enrichment Score (NES) | -1.6188982 |
| Nominal p-value | 0.0022172949 |
| FDR q-value | 0.21687208 |
| FWER p-Value | 0.526 |
| PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|---|
| 1 | RELN | 6510037 | 5307 | 0.035 | -0.2809 | No | ||
| 2 | VLDLR | 870722 3060047 5340452 6550131 | 5740 | 0.027 | -0.3005 | No | ||
| 3 | MAP2K7 | 2260086 | 6457 | 0.019 | -0.3366 | No | ||
| 4 | GRIN2A | 6550538 | 6663 | 0.017 | -0.3454 | No | ||
| 5 | DAB1 | 2060193 7000605 | 7083 | 0.014 | -0.3661 | No | ||
| 6 | PIK3R1 | 4730671 | 7321 | 0.013 | -0.3772 | No | ||
| 7 | PAFAH1B1 | 4230333 6420121 6450066 | 8128 | 0.009 | -0.4194 | No | ||
| 8 | AKT1 | 5290746 | 9329 | 0.005 | -0.4833 | No | ||
| 9 | RAP1A | 1090025 | 11113 | -0.001 | -0.5792 | No | ||
| 10 | GRIN2B | 3800333 | 11884 | -0.003 | -0.6202 | No | ||
| 11 | RAPGEF1 | 60040 4590670 | 12552 | -0.006 | -0.6553 | No | ||
| 12 | MAPT | 360706 1230706 | 13208 | -0.010 | -0.6893 | No | ||
| 13 | ARHGEF2 | 3360577 | 13359 | -0.011 | -0.6960 | No | ||
| 14 | PIK3CA | 6220129 | 13861 | -0.016 | -0.7207 | No | ||
| 15 | LRP8 | 3610746 5360035 | 14160 | -0.022 | -0.7339 | No | ||
| 16 | ITGA3 | 4570427 | 15177 | -0.070 | -0.7795 | No | ||
| 17 | FYN | 2100468 4760520 4850687 | 15761 | -0.130 | -0.7938 | Yes | ||
| 18 | NCK2 | 2510010 | 15947 | -0.156 | -0.7834 | Yes | ||
| 19 | MAPK8 | 2640195 | 16564 | -0.281 | -0.7798 | Yes | ||
| 20 | LRPAP1 | 5570253 | 16733 | -0.330 | -0.7456 | Yes | ||
| 21 | MAP3K11 | 7000039 | 17016 | -0.419 | -0.7059 | Yes | ||
| 22 | CDK5 | 940348 | 17055 | -0.433 | -0.6514 | Yes | ||
| 23 | ITGB1 | 5080156 6270528 | 17164 | -0.478 | -0.5946 | Yes | ||
| 24 | CBL | 6380068 | 17758 | -0.780 | -0.5244 | Yes | ||
| 25 | GSK3B | 5360348 | 17827 | -0.830 | -0.4195 | Yes | ||
| 26 | CRKL | 4050427 | 18189 | -1.245 | -0.2760 | Yes | ||
| 27 | CDK5R1 | 3870161 | 18500 | -2.284 | 0.0062 | Yes |
